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Cheapest GLP-1 Online in May 2026: Every Provider Compared

May 2026 GLP-1 prices across 18 providers. Compounded sema from $149/mo, compounded tirz from $169/mo, brand Wegovy pill from $149/mo direct via NovoCare. Fully compared.

RxPickr Editorial TeamUpdated May 9, 2026

This is the May 2026 snapshot of every GLP-1 medication offering we could price across 18 GLP-1 providers (16 telehealth platforms plus 2 manufacturer-direct programs — LillyDirect and NovoCare), roughly 87 individual SKUs, all verified by direct provider sign-up and pricing-page audits through May 8, 2026. If you want the live, filterable version that updates as providers change prices, head straight to the RxPickr GLP-1 pricing tool. If you want the editorial walkthrough (what's actually cheapest right now and where the best deals hide), read on.

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The cheapest option in May 2026, by category

Here's the headline. One provider rarely wins across every medication category, so we break it down by what you're actually trying to buy.

  • Cheapest compounded semaglutide injection (ongoing): Shed Microdose at $149/month all-inclusive, with no separate membership fee. Mochi Health is right behind at $178/month total ($79 membership + $99 medication).
  • Cheapest compounded tirzepatide injection (ongoing): Enhance.MD's Microdose Tirzepatide at $169/month (1mg/wk dose, $49 first month). Shed Microdose Tirzepatide at $199/month is next.
  • Cheapest brand-name Wegovy: NovoCare Pharmacy at $149/month for the Wegovy pill (1.5mg and 4mg) direct from Novo Nordisk — but it's fulfillment-only and you need to bring your own prescription. Through a telehealth platform, Shed is the cheapest at $274/month total for the Wegovy pill ($149 medication + $125/month Shed Membership), with Found next at $297/month total ($198 medication + $99/month CORE membership on the 12-month plan).
  • Cheapest brand-name Zepbound: LillyDirect at $299/month for the 2.5mg starter dose through the Self Pay Journey Program (per LillyDirect, May 2026). The 5mg dose is $399/mo and 7.5mg–15mg vials are $449/mo within the 45-day refill window.
  • Cheapest Foundayo (orforglipron): LillyDirect at $149/month for the 0.8mg starter dose, direct from Eli Lilly via the Foundayo Self Pay Journey Program — but you need to bring your own prescription. Through a telehealth provider, Found is cheapest at $248/month total ($149 medication + $99/month CORE membership on the 12-month plan). Foundayo medication steps up to $199 at 2.5mg and $299 at 5.5mg–9mg regardless of provider.

Foundayo is worth flagging separately because it's new. The FDA approved orforglipron on April 1, 2026 as the first oral GLP-1 receptor agonist for weight loss without food or water restrictions (FDA, April 2026). It's only been on the market about a month, and pricing is already competitive with compounded options.

Found

$149/mo medication + $99/mo CORE membership = $248/mo total (12-mo plan, May 2026)

Broadest GLP-1 catalog reviewed: compounded sema, tirz, liraglutide, plus Foundayo, Wegovy pill, Wegovy pen, and Zepbound KwikPen. Free insurance check.

Visit Found →

Big picture: how the categories stack up

Step back and the May 2026 market sorts into roughly five price bands:

CategoryPrice rangeNotes
Compounded semaglutide (injection)$149–$297/moThe cheapest broad category. Nearly every telehealth GLP-1 provider offers this. Shed Microdose anchors the floor at $149 all-inclusive; Henry Meds month-to-month sets the upper end at $297.
Compounded tirzepatide (injection)$169–$449/moMeaningfully more expensive than compounded sema. Tirzepatide active pharmaceutical ingredient (API) is harder to source. Enhance.MD Microdose Tirzepatide ($169/mo at 1mg/wk) is the new floor.
Compounded oral / sublingual semaglutide$179–$369/moHenry Meds sublingual at $179/mo is the cheapest non-injection compounded sema. Shed sublingual lozenges and oral drops range $299-$329. MEDVi oral tablets refill at $369. Hers discontinued its $69/mo compounded oral pill in March 2026 after the Novo partnership.
Brand-name Wegovy / Zepbound (cash pay)$149–$499/moNovoCare Pharmacy direct sets the floor: Wegovy pill at $149/mo for 1.5mg/4mg (requires existing Rx). Through telehealth, Shed's Wegovy pill at $274/mo total is the cheapest. Found at $297, Hers/Hims/Ro at $298. LillyDirect Zepbound vials run $299–$449. Hers Zepbound vial reaches $448 with membership.
Foundayo (orforglipron, FDA-approved oral)$149–$348/moBrand-new. Tiered by dose. LillyDirect direct sets the floor at $149/mo for 0.8mg starter (manufacturer-direct, requires existing Rx). Through telehealth: Found cheapest at $248/mo total ($149 starter med + $99 CORE membership on 12-mo plan). Hers and Hims run $298 starter + $149 membership. Higher doses escalate to $299 medication ($398-$448 total).

Compounded liraglutide, a daily-injection GLP-1 that predates semaglutide, is also available. Henry Meds offers it from $179/month all-inclusive (or $119/month if you commit to 12 months paid in full). Found offers it from $149/month medication + $99/month CORE membership = $248/month total. Liraglutide can be a budget alternative for patients who can't tolerate semaglutide.

A note on terminology: "compounded" GLP-1 medications are made by licensed compounding pharmacies and are not FDA-approved as finished products. They contain the same active ingredient as the brand drug, but the finished formulation has not been reviewed by the FDA for safety, efficacy, or quality. The FDA recently took regulatory action narrowing 503B outsourcing pathways for these drugs (FDA, 2025), and most reputable telehealth providers source from 503A pharmacies that compound on a per-prescription basis. We cover the regulatory background in our compounded vs brand-name semaglutide guide.

Cheapest in high-demand sub-categories

Most "cheapest GLP-1" searches actually break into more specific questions. Here's where the deals live in each one.

Cheapest compounded oral or sublingual semaglutide

If injections are a dealbreaker, the cheapest non-injection compounded semaglutide is Shed at $299/month for sublingual lozenges or $329/month for oral drops, both all-inclusive with no separate membership fee. MEDVi offers oral semaglutide tablets at $369/month on refill (with a $249 first month). Hers discontinued its $69/month compounded oral semaglutide pill in March 2026 after striking a deal with Novo Nordisk to focus on brand-name GLP-1s. None of the remaining compounded oral or sublingual products are FDA-approved as finished products. Read the injectable vs oral GLP-1 comparison before committing. Clinical evidence for compounded oral and sublingual formulations is more limited than for injections.

Cheapest no-membership all-inclusive

If you hate the split-billing model where you pay membership plus medication, nine providers in our database bundle everything into a single monthly charge for compounded medications: Henry Meds, TrimRx, Shed, Oak Longevity, Eden, Enhance.MD, MEDVi, Noom Med, and bmiMD. One number, no surprises. (Note: Shed's brand-name medications still require a $125/month Shed Membership; only their compounded products are membership-free. Oak's compounded options are all-inclusive but the headline price applies only at the starter dose; each escalation step adds ~$50-$75.) Found, Mochi Health, Hims, Hers, and Ro all use split billing where medication and membership are charged separately.

Shed

From $149/mo (Microdose) or $175/mo (full-dose, 12-month plan)

All-inclusive compounded semaglutide injection. No separate membership fee. Sublingual and brand-name options also available.

Visit Shed →

Oak Longevity

$183/mo (sema, 3-mo plan starter dose) or $250/mo (tirz, 3-mo plan starter dose); dose-escalating ~$50–$75/step (May 2026)

All-inclusive compounded with no membership and no long-term commitment. Dose-escalation pricing — verify maintenance-dose total before signing up.

Visit Oak Longevity →

Cheapest with insurance

If your insurance covers GLP-1s, or you want the lowest membership fee while you fight for prior authorization, the picture flips. Mochi Health has the lowest standalone membership at $79/month, with copay billed on top through your pharmacy. PlushCare charges $19.99/month for membership when you're using in-network insurance, the lowest of any provider we tracked. Both run insurance-first models and will help with prior authorization paperwork.

For more on the prior auth process, see our GLP-1 insurance coverage guide and prior authorization walkthrough.

Mochi Health

From $79/mo membership

Insurance-first. Lowest standalone membership fee for patients with GLP-1 coverage.

Visit Mochi Health →

Intro and first-month deals worth knowing

Promo pricing has gotten aggressive in May 2026. Five providers are running first-month discounts steep enough to mention.

  • Enhance.MD: $49 first month for compounded semaglutide on the 12-month plan. Ongoing rate: $212/month. This is the lowest entry point in the market right now, and the ongoing rate is also competitive long-term.
  • Enhance.MD: $99 first month for compounded tirzepatide on the 12-month plan. Ongoing rate: $280/month.
  • Noom Med: $99 first month for the GLP-1 Microdose program. Ongoing rate: $199/month. Microdose programs use lower starting doses and tend to suit patients prioritizing tolerability.
  • Eden: $129 first month for compounded semaglutide on the 3-month plan. Ongoing rate: $209/month.
  • MEDVi: $179 first month for compounded semaglutide injection. Ongoing rate: $299/month, a steep jump on refill.

The MEDVi pattern is the one to watch. A $179 first month sounds great until you see the $120 increase on month two. Enhance.MD is the cleaner deal: low entry and competitive ongoing pricing. Always check what month two looks like before you sign up.

Compounded vs brand-name GLP-1 at a glance

Pros

  • Compounded prices start at $149/mo all-inclusive
  • Compounded providers do not require insurance
  • Same active ingredient as brand semaglutide or tirzepatide
  • Most pharmacies ship overnight or 2-day refrigerated

Cons

  • Compounded medications are not FDA-approved as finished products
  • Pricing typically increases as you titrate to higher doses
  • Insurance does not cover compounded GLP-1s
  • Regulatory landscape is evolving and could change provider availability

Notable trends in May 2026

A few things stand out in this month's data versus what we saw earlier in the year:

  • Compounded prices have settled. The $149–$300/month band is now the norm for compounded semaglutide, with the FDA's clarified compounding policy giving the market more stability than it had in late 2024 and early 2025.
  • Microdose programs are emerging as a sub-category. Shed, Noom Med, and Enhance.MD now offer dedicated microdose tracks at $149-$199/month for sema and $169-$199/month for tirz. Enhance.MD's Microdose Tirzepatide at $169/month (1mg/wk) is the cheapest verified compounded tirz option in our database. Microdose programs aim at patients who want lower doses for tolerability or maintenance. This wasn't a thing six months ago.
  • Foundayo is in the market faster than expected. The FDA approved orforglipron on April 1, 2026 (Eli Lilly press release), and as of May, LillyDirect direct, Found, Hers, Hims, Ro, and Shed are all stocking it. LillyDirect sets the price floor at $149/mo for the 0.8mg starter dose; telehealth providers add their membership on top.
  • All-inclusive bundling is now the modal compounded structure. Nine of the 16 providers we track that offer compounded GLP-1s (Henry Meds, TrimRx, Shed, Eden, Enhance.MD, MEDVi, Noom Med, bmiMD, Oak Longevity) bundle medication, visits, and shipping into a single monthly charge with no separate membership fee. The split medication-plus-membership model still dominates for insurance-coordinated and brand-name-focused providers (Found, Mochi Health, Hims, Hers, Ro, PlushCare, WeightWatchers Clinic).

Enhance.MD

$49 first month, then $212/mo (compounded sema, 12-month plan)

Lowest entry point in the market for compounded sema. Same price at every dose; tirzepatide also $99 first month / $280 ongoing.

Visit Enhance.MD →

Use the live RxPickr pricing tool for current rates

Static articles go stale. Provider pricing changes mid-month, intro deals appear and disappear, and new SKUs (like Foundayo) hit the market with no warning. We built the RxPickr GLP-1 pricing tool to be the live, filterable, always-current source of truth. You can filter by medication type, dose, monthly cost, all-inclusive vs split-billing, and insurance support. Every entry shows the date it was last verified.

All prices in this article were verified by direct provider sign-up on May 4, 2026. We'll publish a fresh snapshot at the start of each month, but if the gap between this article's date and today is more than a few weeks, default to the pricing tool. We update it weekly.

Related reading

Bottom line

If you want the cheapest GLP-1 in May 2026 and you're starting from scratch, here's the breakdown by category. Shed Microdose at $149/month all-inclusive is the verified floor for compounded semaglutide injection, with Mochi Health at $178/month total close behind. Enhance.MD's $49 first month is the lowest entry point if you want to test the waters cheaply, and the $212/month ongoing rate (12-month plan) keeps it competitive long-term. For tirzepatide, Enhance.MD's Microdose Tirzepatide at $169/month is the new cheapest, with Shed Microdose Tirzepatide at $199/month next. For brand-name Wegovy, Shed at $274/month total is the cheapest verified path; for Zepbound, LillyDirect at $299/month for the starter dose. For Foundayo, LillyDirect at $149/month direct from Lilly is the floor (existing prescription required), or Found at $248/month total ($149 medication + $99 CORE membership on the 12-month plan) for full telehealth coverage.

The right answer for your situation depends on whether you have insurance, your dose, your tolerance for compounded vs brand-name medication, and how you feel about long-term commitments. Use the pricing tool to filter to your specifics, or take the quiz for a personalized provider recommendation.