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Cheapest GLP-1 Online in May 2026: Every Provider Compared

May 2026 GLP-1 prices across 16 providers. Compounded sema from $149/mo, brand Wegovy from $198/mo, Foundayo from $149/mo. Fully compared.

RxPickr Editorial Team

This is the May 2026 snapshot of every GLP-1 medication offering we could price across 16 telehealth providers, roughly 60 individual SKUs, all verified by direct provider sign-up between April 28 and May 4, 2026. If you want the live, filterable version that updates as providers change prices, head straight to the RxPickr GLP-1 pricing tool. If you want the editorial walkthrough (what's actually cheapest right now and where the best deals hide), read on.

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The cheapest option in May 2026, by category

Here's the headline. One provider rarely wins across every medication category, so we break it down by what you're actually trying to buy.

  • Cheapest compounded semaglutide injection (ongoing): Found and Shed Microdose tied at $149/month all-inclusive.
  • Cheapest compounded tirzepatide injection (ongoing): Shed Microdose at $199/month all-inclusive.
  • Cheapest brand-name Wegovy total cost: Found at $198/month for the Wegovy pill, all-inclusive, no separate membership fee.
  • Cheapest brand-name Zepbound: LillyDirect at $299/month for the 2.5mg starter dose through the Self Pay Journey Program (per LillyDirect, May 2026). The 5mg dose is $399/mo and 7.5mgโ€“15mg vials are $449/mo within the 45-day refill window.
  • Cheapest Foundayo (orforglipron): Found at $149/month for the 0.8mg starter dose. The price steps up to $199/month at Day 31 and $299/month at maintenance doses.

Foundayo is worth flagging separately because it's new. The FDA approved orforglipron on April 1, 2026 as the first oral GLP-1 receptor agonist for weight loss without food or water restrictions (FDA, April 2026). It's only been on the market about a month, and pricing is already competitive with compounded options.

Found

From $149/mo

Cheapest all-inclusive compounded sema, plus Wegovy pill at $198/mo and Foundayo at $149/mo starter.

Visit Found โ†’

Big picture: how the categories stack up

Step back and the May 2026 market sorts into roughly five price bands:

CategoryPrice rangeNotes
Compounded semaglutide (injection)$149โ€“$299/moThe cheapest broad category. Nearly every telehealth GLP-1 provider offers this.
Compounded tirzepatide (injection)$199โ€“$449/moMeaningfully more expensive than compounded sema. Tirzepatide active pharmaceutical ingredient (API) is harder to source.
Compounded oral / sublingual semaglutide$218โ€“$369/moNiche but growing. Hers is the cheapest pill option; MEDVi tablets and Shed sublingual sit at the upper end.
Brand-name Wegovy / Zepbound (cash pay)$198โ€“$449/moFound's Wegovy pill bundle is the outlier; everything else starts $300+.
Foundayo (orforglipron, FDA-approved oral)$149โ€“$299/moBrand-new. Tiered by dose. Competitive at low doses, comparable to brand at maintenance.

Compounded liraglutide, a daily-injection GLP-1 that predates semaglutide, is also available at Found from $149/month as a budget alternative for patients who can't tolerate semaglutide.

A note on terminology: "compounded" GLP-1 medications are made by licensed compounding pharmacies and are not FDA-approved as finished products. They contain the same active ingredient as the brand drug, but the finished formulation has not been reviewed by the FDA for safety, efficacy, or quality. The FDA recently took regulatory action narrowing 503B outsourcing pathways for these drugs (FDA, 2025), and most reputable telehealth providers source from 503A pharmacies that compound on a per-prescription basis. We cover the regulatory background in our compounded vs brand-name semaglutide guide.

Cheapest in high-demand sub-categories

Most "cheapest GLP-1" searches actually break into more specific questions. Here's where the deals live in each one.

Cheapest compounded oral or sublingual semaglutide

If injections are a dealbreaker, Hers wins at $218/month total ($69 medication + $149 membership) for compounded oral semaglutide pills, with a 10-month commitment. Shed is the closest alternative at $299/month for sublingual lozenges or $329/month for oral drops. None of these are FDA-approved as finished products. Read the injectable vs oral GLP-1 comparison before committing. Clinical evidence for compounded oral and sublingual formulations is more limited than for injections.

Cheapest no-membership all-inclusive

If you hate the split-billing model where you pay membership plus medication, eight providers in our database bundle everything into a single monthly charge: Henry Meds, TrimRx, Found, Shed, Eden, Enhance.MD, MEDVi, and Noom Med. One number, no surprises.

Shed

From $149/mo (Microdose) or $175/mo (full-dose, 12-month plan)

All-inclusive compounded semaglutide injection. No separate membership fee. Sublingual and brand-name options also available.

Visit Shed โ†’

Cheapest with insurance

If your insurance covers GLP-1s, or you want the lowest membership fee while you fight for prior authorization, the picture flips. Mochi Health has the lowest standalone membership at $79/month, with copay billed on top through your pharmacy. PlushCare charges $19.99/month for membership when you're using in-network insurance, the lowest of any provider we tracked. Both run insurance-first models and will help with prior authorization paperwork.

For more on the prior auth process, see our GLP-1 insurance coverage guide and prior authorization walkthrough.

Mochi Health

From $79/mo membership

Insurance-first. Lowest standalone membership fee for patients with GLP-1 coverage.

Visit Mochi Health โ†’

Intro and first-month deals worth knowing

Promo pricing has gotten aggressive in May 2026. Five providers are running first-month discounts steep enough to mention.

  • Enhance.MD: $49 first month for compounded semaglutide on the 12-month plan. Ongoing rate: $212/month. This is the lowest entry point in the market right now, and the ongoing rate is also competitive long-term.
  • Enhance.MD: $99 first month for compounded tirzepatide on the 12-month plan. Ongoing rate: $280/month.
  • Noom Med: $99 first month for the GLP-1 Microdose program. Ongoing rate: $199/month. Microdose programs use lower starting doses and tend to suit patients prioritizing tolerability.
  • Eden: $129 first month for compounded semaglutide on the 3-month plan. Ongoing rate: $209/month.
  • MEDVi: $179 first month for compounded semaglutide injection. Ongoing rate: $299/month, a steep jump on refill.

The MEDVi pattern is the one to watch. A $179 first month sounds great until you see the $120 increase on month two. Enhance.MD is the cleaner deal: low entry and competitive ongoing pricing. Always check what month two looks like before you sign up.

Compounded vs brand-name GLP-1 at a glance

Pros

  • Compounded prices start at $149/mo all-inclusive
  • Compounded providers do not require insurance
  • Same active ingredient as brand semaglutide or tirzepatide
  • Most pharmacies ship overnight or 2-day refrigerated

Cons

  • Compounded medications are not FDA-approved as finished products
  • Pricing typically increases as you titrate to higher doses
  • Insurance does not cover compounded GLP-1s
  • Regulatory landscape is evolving and could change provider availability

Notable trends in May 2026

A few things stand out in this month's data versus what we saw earlier in the year:

  • Compounded prices have settled. The $149โ€“$300/month band is now the norm for compounded semaglutide, with the FDA's clarified compounding policy giving the market more stability than it had in late 2024 and early 2025.
  • Microdose programs are emerging as a sub-category. Both Shed and Noom Med now offer dedicated $149โ€“$199/month "microdose" tracks aimed at patients who want lower doses for tolerability or maintenance. This wasn't a thing six months ago.
  • Foundayo is in the market faster than expected. The FDA approved orforglipron on April 1, 2026 (Eli Lilly press release), and as of May, both Found and Shed are already offering it through their telehealth platforms at competitive prices.
  • All-inclusive bundling is winning. Eight of the 16 providers we tracked now bundle medication + visits + shipping into one charge. The split medication-plus-membership model is increasingly the minority structure.

Enhance.MD

$49 first month, then $212/mo (compounded sema, 12-month plan)

Lowest entry point in the market for compounded sema. Same price at every dose; tirzepatide also $99 first month / $280 ongoing.

Visit Enhance.MD โ†’

Use the live RxPickr pricing tool for current rates

Static articles go stale. Provider pricing changes mid-month, intro deals appear and disappear, and new SKUs (like Foundayo) hit the market with no warning. We built the RxPickr GLP-1 pricing tool to be the live, filterable, always-current source of truth. You can filter by medication type, dose, monthly cost, all-inclusive vs split-billing, and insurance support. Every entry shows the date it was last verified.

All prices in this article were verified by direct provider sign-up on May 4, 2026. We'll publish a fresh snapshot at the start of each month, but if the gap between this article's date and today is more than a few weeks, default to the pricing tool. We update it weekly.

Related reading

Bottom line

If you want the cheapest GLP-1 in May 2026 and you're starting from scratch, here's the breakdown by category. Compounded semaglutide injection at $149/month all-inclusive from Found or Shed is the floor for ongoing pricing. Enhance.MD's $49 first month is the lowest entry point if you want to test the waters cheaply, and the $212/month ongoing rate keeps it competitive after the intro period. For tirzepatide, Shed Microdose at $199/month is the cheapest. For brand-name medication, Found's Wegovy pill at $198/month is the surprise winner; for Zepbound, it's LillyDirect at $299/month for the starter dose. For Foundayo, Found at $149/month for the starter dose.

The right answer for your situation depends on whether you have insurance, your dose, your tolerance for compounded vs brand-name medication, and how you feel about long-term commitments. Use the pricing tool to filter to your specifics, or take the quiz for a personalized provider recommendation.